Institution Type Public University

Is there a medical school? Yes

Is this a land-grant institution? Yes

Vivarium Director Dr. Laurie L Brignolo, DACLAM

Program Director Dr. Laurie L Brignolo, DACLAM

Who to Contact llbrignolo@ucdavis.edu

Address line 1 Center for Laboratory Animal Science

Address line 2 School of Veterinary Medicine

Address line 3 University of California, Davis

City Davis

State CA

Zip 95616

Phone 530-752-5836

Fax 530-754-5667

Email llbrignolo@ucdavis.edu

Vivarium Name Center for Laboratory Animal Science

Is the facility AAALAC accredited? Yes

Describe management structure More than 5 administratively distict vivaria

Describe the extent to which your facilities are centralized Animals housed in 5+ separate locations

Vivarium Square Feet 180000

Summarize the nature of the animal population and the predominant types of clinical activities Campus Veterinary Services (CVS) provides veterinary oversight for the diverse population of animals used in research and teaching at UC Davis. This includes ectotherms, fish, livestock, and the typical research animals. There is a large rodent barrier facility that maintains production colonies of genetically modified mice. The California National Primate Center (CNPRC) houses over 5200 NHP with research emphasis in reproductive biology, HIV/AIDS, asthma, and neurodegenerative disorders. The Comparative Pathology Laboratory (CPL) provides diagnostic support to investigators at UCD and provides in-house health monitoring tests. Residents do four 3 month long clinical rotations usually during the first 12 - 15 months of the program spend the first 9 months in rotations amoungst the 3 areas, additional 1 -4 month long clinical rotations in primate pathology, fish health and at a targetted mutant mouse production facility along with a research project are completed in the remaining 14 - 17 months of the program.

Number of Veterinarians in program 10

Number of ACLAM Diplomates in program 6

Number of Boarded Pathologists 4

Number of Other Boarded Veterinary Specialists 2

Number of necropsies/week in the veterinary unit 50

Number of surgical cases/week in the veterinary unit 3

Is this program recognized by ACLAM? Yes

Does this program participate in the Uniform Application Process? No

Number of concurrent residents 1

How many residents/trainees have completed this program? 0

Of these, how many have subsequently become ACLAM Diplomates? 29

In what year did the program accept its first trainee? 1970

How many years are required to complete this program (residency only)? 2

Is formal coursework offered? Yes

Is a degree program associated with this residency? No

If yes, what degree(s)? Ph.D., M.S., M.P.V.M. are possible but separate

Which departments most commonly grant degree(s)? Graduate Group in Comparative Pathology, Epidemiology

Give an overview of this program, describing its particular strengths and any unique aspects that are not addressed in any of the other sections UCD has a medical school, veterinary school, National Primate Research Center, School of Agriculture, veterinary extension, Department of Psychology and College of Biological Sciences that have researchers using animals. In addition there are a number of core units including the Center for Comparative Medicine, the Comparative Pathology Laboratory, and the Mouse Biology Program that collaborate with investigators across campus using animal models. Trainees participate in veterinary reviews of animal care and use protocols (>1400 active protocols) that cover a wide range of research and teaching activities. These are good tools to review all aspects of regulatory compliance.

Describe any unique research interests of your faculty Residents are expected to work with established researchers to develop and execute a research project acceptable for publication prior to completion of their resident training. Residents often select their research mentor during their first year of training. Primate focused residents usually work on clinically focused projects under the direction of the senior clinical veterinarians at the CNNPRC, while traditional lab animal focused residents may work with investigators they meet through their clinical veterinary activities, on recommendation of the Director of CLAS, or through academic contacts or as the result of animal use protocol review.

Give a few literature citations of publications completed by trainees during their tenure in this program 1: Ma, B W, Bokulich, NA, Castillo, PA, Kananurak, A, Underwood, MA, Mills, DA, Bevins, CA. "Routine Habitat Change: A Source of Unrecognized Transient Alteration of Intestinal Microbiota in Laboratory Mice" 2013. PLoS ONE 7:e47416. 2. Weiss, EE, Evan, KD, Griffey, SM ""Comparison of Fur Mite PCR and Tape Test for Initial and Post-Treatment Diagnosis During a Natural Infection" 2013 JAALAS 51(5): 574 -578. 3. Kelly, KR, Pypendop, BH, Grayson, JK, Stanley, SD, Christe, KL, Lerche, NW. "Pharmacokinetics of oxymorphone in titi monkeys (Callicebus spp.) and rhesus macaques (Macaca mulatta)" 2011. JAALAS 50(2):212-20. 4. Adamson, TA, Kendall, LV, Goss, SL, Grayson, K, Touma, C, Palme, R, Chen, JQ, Borowski, AD. "Assessment of Carprofen an Buprenorphine on Recovery of Mice after Surgical Removal of the Mammary Fat Pad" 2010. JAALAS 49(5):610 - 616. 5. MacGuire JG, Christe KL, Yee JL, Kalman-Bowlus AL, Lerche NW. Serologic evaluation of clinical and subclinical secondary hepatic amyloidosis in rhesus macaques (Macaca mulatta). Comp Med 2009 Apr;59(2): 168-73. 6. Effects of the macrolide drug tylosin on chronic diarrhea in rhesus macaques (Macaca mulatta). Blackwood RS, Tarara RP, Christe KL, Spinner A, Lerche NW. Comp Med 2008 Feb;58(1):81-7. 7.Evans KD, Hewett TA, Clayton CJ, Krubitzer LA, Griffey SM. Normal Organ Weights, Serum Chemistry, Hematology, and Cecal and Nasopharyngeal Bacterial Cultures in the Gray Short-Tailed Opossum (Monodelphis domestica). J Am Assoc Lab Anim Sci. 2010;49(4):401-6. PubMed PMID: 20819383.

Where will vacancies be advertised? UCD Veterinary Medical Teaching Hospital website

What month does the program begin? July 1

Starting Annual Salary 0

To what extent is travel to meetings, etc. paid for? One meeting per year

Is individual health insurance provided? Yes

Is family health insurance provided? Yes

Describe any fees or tuition Parking pass necessary for residents at the CNPRC

Describe the residents’ responsibilities for night, weekend, and holiday coverage Residents rotate night, weekend and holiday coverage with staff veterinarians.

How many annual vacation days are given? 24

How many annual sick days are given? 25

Briefly describe the community Davis is located in the Central Valley of Northern California and is two hours from great skiing at Lake Tahoe and two hours from great beaches in the Bay area.

Institutional, facility, or training program web site http://www.vetmed.ucdavis.edu/vmth/residency_info/lab_animal.cfm