Institution TypePublic University
Is there a medical school?Yes
Is this a land-grant institution?No
Vivarium DirectorDr. David Hamilton
Program DirectorDr. David Hamilton
Who to ContactDr. David Hamilton
Address956 Court Ave Room B106, Memphis, TN  38163
Phone(901) 448-5451
Fax(901) 448-8506

Vivarium Information

Vivarium NameLaboratory Animal Care Unit
Is the facility AAALAC accredited?Yes
Describe management structureOne centrally managed vivarium
Describe the extent to which your facilities are centralizedAnimals housed in 6 separate locations
Vivarium Square Feet90,000
Summarize the nature of the animal population and the predominant types of clinical activities

mice, rats, hamsters, pigs, rabbits, ferrets, guinea pigs

Number of Veterinarians in program6
Number of ACLAM Diplomates in program4
Number of Boarded Pathologists1
Number of Other Boarded Veterinary Specialists0
Number of necropsies/week in the veterinary unit0
Number of surgical cases/week in the veterinary unit0

Training Program Details

Is this program recognized by ACLAM?Yes
Does this program participate in the Veterinary Internship & Residency Matching Program (VIRMP)?Yes
Number of concurrent residents2
How many residents/trainees have completed this program?14
Of these, how many have subsequently become ACLAM Diplomates?8
In what year did the program accept its first trainee?1983
How many years are required to complete this program (residency only)?3
Is formal coursework offered?Yes
Is a degree program associated with this residency?No
If yes, what degree(s)?
Which departments most commonly grant degree(s)?
Give an overview of this program, describing its particular strengths and any unique aspects that are not addressed in any of the other sections

Approximately 70% of the trainee’s time is devoted to clinical residency training in laboratory animal science and medicine consisting primarily of participation in clinical rotations, facility management, and teaching/training programs (AALAS Technician Training, research investigator training, and seminars on topics related to laboratory animal science and medicine). Courses are provided by the Department of Comparative Medicine include: Laboratory Animal Resources, Essentials of Animal Experimentation (CMED 711), and Biology and Pathophysiology of Lab Animals (CMED 712 & 713). The trainee gains clinical experience through interaction with the veterinarians on the training faculty, investigators, and technicians as problems are encountered and solved.

With the opening of the Regional Biocontainment Laboratory, trainees will receive basic and advanced training in biosafety and animal biosafety that will prepare them for working in an ABSL3 facility.

Describe any unique research interests of your facultyMajor areas of emphasis by the UTHSC faculty include pharmacology and drug development, cardiovascular disease, neuroscience, cancer pathogenesis and treatment, addiction and substance abuse, diabetes, infectious disease including COVID-19, and aging.
Give a few literature citations of publications completed by trainees during their tenure in this program
  1. Importance of heat-labile enterotoxin in colonization of the adult mouse small intestine by human enterotoxigenic Escherichia coli strains. Allen KP, Randolph MM, Fleckenstein JM. Infect Immun. 2006 Feb;74(2):869-75.
  2. Efficacy and safety of topical selamectin to eradicate pinworm (Syphacia spp.) infections in rats (Rattus norvegicus) and mice (Mus musculus). Hill WA, Randolph MM, Lokey SJ, Hayes E, Boyd KL, Mandrell TD. J Am Assoc Lab Anim Sci. 2006 May;45(3):23-6.
  3. Posterior paresis and osteolysis in guinea pigs (Cavia porcellus) secondary to Freund's adjuvant immunization. Hill WA, Boyd KL, Ober CP, Farrar PL, Mandrell TD. J Am Assoc Lab Anim Sci. 2006 Mar;45(2):53-6.
  4. Effects of leukotriene inhibition on pulmonary morphology in rat pup lungs exposed to hyperoxia.
    Funk AJ, Mandrell TD, Lokey SJ, Kosanke SD, Li CS, Potters CF. Comp Med. 2007 Apr;57(2):186-92.
  5. The EtpA exoprotein of enterotoxigenic Escherichia coli promotes intestinal colonization and is a protective antigen in an experimental model of murine infection. Roy K, Hamilton D, Allen KP, Randolph MP, Fleckenstein JM. Infect Immun. 2008 May;76(5):2106-12.
  6. Targeted deletion of GD3 synthase protects against MPTP-induced neurodegeneration. Akkhawattanangkul Y, Maiti P, Xue Y, Aryal D, Wetsel WC, Hamilton D, Fowler SC, McDonald MP. Genes Brain Behav. 2017 Jun; 16(5):522-536.
  7. Eyedrop Inoculation Causes Sublethal Leptospirosis in Mice. Sullivan JP, Nair N, Potula HH, Gomes-Solecki M. Infect Immun. 2017 Mar 23;85(4): e01050-16.
  8. Evaluation of In-cage Filter Paper as a Replacement for Sentinel Mice in the Detection of Murine Pathogens. O’Connell, Kathryn A; Tigyi, Gabor J; Livingston, Robert S; Johnson, Daniel L; Hamilton, David J. JAALAS. 2021 Feb 24. doi: 10.30802/AALAS-JAALAS-20-000086
Where will vacancies be advertised?VIRMP or through AALAS Career Center
What month does the program begin?July

Living and Working

Starting Annual SalaryBased on NIH scale
To what extent is travel to meetings, etc. paid for?

Residents are allowed travel to 1 meeting per year in which scientific information is being presented.

Is individual health insurance provided?Yes
Is family health insurance provided?Yes
Describe any fees or tuition
Describe the residents' responsibilities for night, weekend, and holiday coverageRotational weekend and holiday on-call
How many annual vacation days are given?24
How many annual sick days are given?12
Briefly describe the community

The UTHSC campus is located in the heart of midtown Memphis, Tennessee. With a population of close to 700,000, Memphis is an incredible place to live, work and study. Memphis is located on the Mississippi River and is famous for the influential strains of blues, soul and rock 'n' roll music, along with world’s best BBQ! Memphis is a diverse city and hosts several annual festivals, the largest of which is the Memphis in May International Festival.

Memphis typically enjoys a pleasant climate with mild winters, hot summers and beautiful springs and falls.
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